Mitigating morphine dependence and withdrawal: The role of venlafaxine and calcium channel blockers in mitochondrial damage and oxidative stress in the brain
Coadministration of venlafaxine with calcium channel blockers could reduce morphine withdrawal symptoms and prevent its pathological damage. The suggested mechanism of this event is preventing mitochondrial damage and oxidative stress induced by morphine.
Authors
- Behnam Ghorbanzadeh (ORCID: https://orcid.org/0000-0002-0409-0416)
- Ali Akbar Oroojan (ORCID: https://orcid.org/0000-0001-5249-3239)
- Mohammad Amin Behmanesh (ORCID: https://orcid.org/0000-0002-4292-5381)
- Faezeh Fallah (ORCID: https://orcid.org/0000-0002-7115-9161)
- Radman Amiri
- Soheila Alboghobeish
Institutions
- Dezful University of Medical Sciences (IR)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111364
- Citations
- 5
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 4.55
Funders
- Dezful University of Medical Sciences