Exploration of biomarkers for inhibitor development in persons with hemophilia A
These findings highlight the association of inhibitor presence with altered plasma cytokine levels and <i>N-</i>glycosylation patterns. Prospective validation is crucial to confirm these associations, develop robust biomarkers, and improve inhibitor risk assessment for persons with HA.
Authors
- Mengni Fan (ORCID: https://orcid.org/0009-0006-2466-1438)
- Barbara A. Konkle (ORCID: https://orcid.org/0000-0002-3959-8797)
- Ting-Yen Chao
- Carol H. Miao (ORCID: https://orcid.org/0000-0001-6520-2373)
- Anna Faino (ORCID: https://orcid.org/0000-0001-9427-9548)
- Sheng Bao (ORCID: https://orcid.org/0000-0003-2026-8058)
- Weidong Xiao (ORCID: https://orcid.org/0000-0002-9300-980X)
- Tangliang Shen
- Marilyn J. Manco‐Johnson (ORCID: https://orcid.org/0000-0001-5215-1482)
- Lei Li (ORCID: https://orcid.org/0000-0001-5304-8380)
- Junping Zhang (ORCID: https://orcid.org/0000-0002-7271-8615)
- Xiaohe Cai
Institutions
- Georgia State University (US)
- University of Washington (US)
- Cancer Research And Biostatistics (US)
- Seattle Children's Hospital (US)
- Washington Center (US)
- University of Colorado Anschutz Medical Campus (US)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1016/j.rpth.2025.102877
- Citations
- 2
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 3.54