Therapeutic effect of nintedanib in orbital fibroblasts in patients with Graves’ orbitopathy
Nintedanib suppressed profibrotic protein production, adipogenesis, and hyaluronan production in <i>in vitro</i>. These findings indicate the potential therapeutic efficacy of nintedanib in GO management.
Authors
- JaeSang Ko (ORCID: https://orcid.org/0000-0002-3011-7213)
- Jin Sook Yoon (ORCID: https://orcid.org/0000-0002-8751-9467)
- Soo Hyun Choi (ORCID: https://orcid.org/0000-0003-1421-5283)
- Hyun Young Park
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1080/08923973.2025.2491554
- Primary Topic
- Ophthalmology and Eye Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation of Korea
- Yonsei University College of Medicine