ESTABLISHMENT OF THE 6-SHOGAOL EXTRACTION PROCESS FROM 6-SHOGAOL-ENRICHED GINGER FOR CANCER TREATMENT

Objectives: To optimally extract the potential phytochemical “6-shogaol” from fermented shogaol-enriched ginger. Methods: Extraction process parameters were investigated using 6-shogaol as a marker. Results: The suitable parameters of the 6-shogaol extraction process: Hot extraction using reflux equipment, solvent of 90% ethanol, solvent/herb ratio of 15/1, temperature of 70ºC, duration of 90 minutes, and two-time extraction. The 6-shogaol extraction efficiency was 89.61 ± 0.68%. Conclusion: The optimal process for 6-shogaol extraction from fermented shogaol-enriched ginger has been studied.