Urinary cotinine levels versus self-reported smoking status for assessing placental abruption risk: the Japan Environment and Children’s study
Elevated urinary cotinine levels during pregnancy were significantly associated with an increased risk of placental abruption, whereas self-reported smoking status was not. Urinary cotinine levels are a more accurate and clinically reliable biomarker to assess smoking-related risks during pregnancy than self-reported smoking status. Future research should explore the relationship between urinary cotinine levels and other obstetric complications to validate its utility as a comprehensive pregnancy biomarker.
Authors
- Shun Yasuda (ORCID: https://orcid.org/0000-0002-6520-902X)
- Hyo Kyozuka (ORCID: https://orcid.org/0000-0001-7782-3396)
- Hidekazu Nishigori (ORCID: https://orcid.org/0000-0001-6726-2193)
- Toma Fukuda (ORCID: https://orcid.org/0000-0002-5735-389X)
- Koichi Hashimoto (ORCID: https://orcid.org/0000-0001-7186-7603)
- Seiji Yasumura (ORCID: https://orcid.org/0000-0002-4715-2840)
- Akiko Yamaguchi (ORCID: https://orcid.org/0000-0002-5331-5490)
- Yuka Ogata (ORCID: https://orcid.org/0009-0008-4827-4381)
- Mitsuaki Hosoya (ORCID: https://orcid.org/0000-0003-1626-3625)
- Keiya Fujimori (ORCID: https://orcid.org/0000-0001-8618-4063)
- Tsuyoshi Murata (ORCID: https://orcid.org/0000-0001-9506-117X)
- Akiko Satô (ORCID: https://orcid.org/0000-0002-1279-4026)
Institutions
- Fukushima Medical University (JP)
- Center for Children (US)
- Fukushima Prefectural Culture Center (JP)
Publication Details
- Journal
- The Journal of Maternal-Fetal & Neonatal Medicine
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1080/14767058.2025.2497059
- Primary Topic
- Smoking Behavior and Cessation
- Type
- article
- Field-Weighted Citation Impact
- 0.00