A subtype‐selective photoswitchable agonist for precise manipulation of GABA<sub>A</sub> receptors
GABA<sub>A</sub>Rs are potential therapeutic targets for many disorders. However, their physiological and pathophysiological roles remain largely unexplored. Az-IGU may enable photopharmacological studies of α4/6β3δ GABA<sub>A</sub>Rs, providing new opportunities for biomedical and neurobiological applications.
Authors
- Jay‐Ron Lee
- Wan‐Chen Lin (ORCID: https://orcid.org/0000-0001-7842-3036)
- Simon Miguel M. Lopez (ORCID: https://orcid.org/0000-0001-7353-7376)
Institutions
- National Yang Ming Chiao Tung University (TW)
- Institute of Biomedical Sciences, Academia Sinica (TW)
- Academia Sinica (TW)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1111/bph.70066
- Citations
- 1
- Primary Topic
- Photochromic and Fluorescence Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.52