Circulating linoleic acid and its interplay with gut microbiota during pregnancy for gestational diabetes mellitus
Our study provides evidence for an inverse causal association between plasma LA levels during pregnancy and GDM risk, which is both mediated and modified by gut microbiota.
Authors
- Xiangwang He
- Yichao Huang (ORCID: https://orcid.org/0000-0003-1186-1300)
- Ping Wu (ORCID: https://orcid.org/0000-0001-5718-9922)
- Yayi Hu (ORCID: https://orcid.org/0000-0001-6865-2388)
- Ping Hu
- Xiong‐Fei Pan (ORCID: https://orcid.org/0000-0002-9350-9230)
- Shizhuo Yang
- Jiahui Qiu (ORCID: https://orcid.org/0000-0003-4795-5536)
- Yunhaonan Yang
- Nianwei Wu
- Peiqi Zhang (ORCID: https://orcid.org/0000-0001-7649-6338)
- Tianlei Wang (ORCID: https://orcid.org/0000-0002-4498-4326)
- Fengjiang Sun (ORCID: https://orcid.org/0000-0002-9002-0173)
- Fan Li (ORCID: https://orcid.org/0000-0002-2034-9600)
- Shuo Li (ORCID: https://orcid.org/0000-0003-2331-2448)
- Da Chen (ORCID: https://orcid.org/0000-0001-5563-0091)
- Xiaojuan Liu (ORCID: https://orcid.org/0000-0003-3894-7550)
- Shanshan Zhang
- Gang Liu (ORCID: https://orcid.org/0000-0001-5917-9605)
- Yibin Wang (ORCID: https://orcid.org/0000-0003-0852-0767)
- Jason Wu (ORCID: https://orcid.org/0000-0003-2073-3562)
- Jiaying Yuan
- Yu‐Wei Lai
- Yidan Dong
- An Pan (ORCID: https://orcid.org/0000-0002-1089-7945)
Institutions
- Albert Einstein College of Medicine (US)
- Jinan University (CN)
- Anhui Medical University (CN)
- Chengdu Medical College (CN)
- Sichuan University (CN)
- UNSW Sydney (AU)
- The George Institute for Global Health (AU)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1186/s12916-025-04061-7
- Citations
- 4
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 8.23
Funders
- National Natural Science Foundation of China
- Huazhong University of Science and Technology
- Tongji University
- Sichuan University
- Natural Science Foundation of Sichuan Province
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities
- National Science Fund for Distinguished Young Scholars