Preparation of Fortified Edible Gelatin Films Nanoscale Magnesium Oxide and Study of It's Mechanical and Antibacterial Effectiveness

Membranes were prepared from laboratory bovine gelatin with polyvinyl alcohol in fixed proportions of 1/1 (wt/wt), using plasticizers (glycerol and sorbitol), adding magnesium oxide nanoparticles to them, and comparing them to unreinforced membranes, and measuring the mechanical properties of these membranes, which were the thickness of the membrane and tensile capacity. In addition to elongation, solubility, and antimicrobial activity. It was noted that the thickness of laboratory bovine gelatin membranes supported with magnesium oxide nanoparticles is 30 mm, which is more than the thickness of the unsupported gelatin membrane, which is 6 mm. The results indicated that the greatest tensile strength (γM Scma Max) that the model could withstand (the strength of the model) was for the membrane made from laboratory gelatin with 1 gm of polyvinyl alcohol (PVA), 18 gm of glycerol, and 10 ml of nano solution, and it reached 117 MPa with a pouring ratio of 10 ml. However, the lowest tensile strength (σM) was 0.0705 MPa for the membrane made from laboratory gelatin with 1 gm polyvinyl alcohol PVA, 18 gm glycerol, and 10 ml of nano solution with a casting ratio of 15 ml, and the best flexibility (the greatest elongation) (Epsilon At break (εM % Upsilon at break) was for the membrane made from laboratory gelatin with 1 g of polyvinyl alcohol (PVA), 18 g of glycerol, and 10 ml of nano solution, and it reached 117 MPa with a pouring ratio of 43.3 with 10 ml. It was noted that the solubility of the membranes supported with magnesium oxide nanoparticles was lower than the solubility of the membranes not supported with magnesium oxide nanoparticles. It was found that there was a high inhibitory activity for nanogelatin membrane solutions compared to membrane solutions not supported by nanoparticles against all types of selected pathogenic bacteria. The highest inhibitory activity obtained for the nanogelatin membrane was against Staphylococcus aureus bacteria, then against Esherichia coli and Pseudomonas aeruginosa bacteria, respectively, although less. The effect of gelatin film on Esherichia coli bacteria.

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Publication Details

Journal
University of Thi-Qar Journal Of Medicine
Published
2024-11-13
DOI
https://doi.org/10.32792/jmed.v28i2.591
Primary Topic
Electrospun Nanofibers in Biomedical Applications
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article
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article

Preparation of Fortified Edible Gelatin Films Nanoscale Magnesium Oxide and Study of It's Mechanical and Antibacterial Effectiveness

Hisham Faiadh Mohammad, Eman Kadhem Jawad, Khadeeja Sadiq Jaffer
University of Thi-Qar Journal Of Medicine
Electrospun Nanofibers in Biomedical Applications
article

Preparation of Fortified Edible Gelatin Films Nanoscale Magnesium Oxide and Study of It's Mechanical and Antibacterial Effectiveness

Hisham Faiadh Mohammad, Eman Kadhem Jawad, Khadeeja Sadiq Jaffer
article en

Abstract

Membranes were prepared from laboratory bovine gelatin with polyvinyl alcohol in fixed proportions of 1/1 (wt/wt), using plasticizers (glycerol and sorbitol), adding magnesium oxide nanoparticles to them, and comparing them to unreinforced membranes, and measuring the mechanical properties of these membranes, which were the thickness of the membrane and tensile capacity. In addition to elongation, solubility, and antimicrobial activity. It was noted that the thickness of laboratory bovine gelatin membranes supported with magnesium oxide nanoparticles is 30 mm, which is more than the thickness of the unsupported gelatin membrane, which is 6 mm. The results indicated that the greatest tensile strength (γM Scma Max) that the model could withstand (the strength of the model) was for the membrane made from laboratory gelatin with 1 gm of polyvinyl alcohol (PVA), 18 gm of glycerol, and 10 ml of nano solution, and it reached 117 MPa with a pouring ratio of 10 ml. However, the lowest tensile strength (σM) was 0.0705 MPa for the membrane made from laboratory gelatin with 1 gm polyvinyl alcohol PVA, 18 gm glycerol, and 10 ml of nano solution with a casting ratio of 15 ml, and the best flexibility (the greatest elongation) (Epsilon At break (εM % Upsilon at break) was for the membrane made from laboratory gelatin with 1 g of polyvinyl alcohol (PVA), 18 g of glycerol, and 10 ml of nano solution, and it reached 117 MPa with a pouring ratio of 43.3 with 10 ml. It was noted that the solubility of the membranes supported with magnesium oxide nanoparticles was lower than the solubility of the membranes not supported with magnesium oxide nanoparticles. It was found that there was a high inhibitory activity for nanogelatin membrane solutions compared to membrane solutions not supported by nanoparticles against all types of selected pathogenic bacteria. The highest inhibitory activity obtained for the nanogelatin membrane was against Staphylococcus aureus bacteria, then against Esherichia coli and Pseudomonas aeruginosa bacteria, respectively, although less. The effect of gelatin film on Esherichia coli bacteria.

University of Thi-Qar Journal Of MedicineVol. 28(2)
University of Basrah (IQ)
Openalex Percentile: Top 87%
Electrospun Nanofibers in Biomedical Applications
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