Clinical pathological characteristics and prognostic analysis of renal primitive neuroectodermal tumours: a multicentre retrospective study of 16 cases in Northwest China
The absence of rosette structures does not exclude the diagnosis of rPNET. BCL-2 and Ki-67 expression are significant prognostic factors, with high Ki-67 expression and negative BCL-2 expression associated with worse outcomes. These findings highlight the importance of molecular markers in risk stratification and treatment planning for rPNET.
Authors
- Xilian Zhao
- Bo Guo (ORCID: https://orcid.org/0000-0001-7723-6984)
- Jiayan Liu (ORCID: https://orcid.org/0000-0003-2798-8795)
- Mingyu Shao (ORCID: https://orcid.org/0000-0003-2367-5097)
- Zhenzhen Li (ORCID: https://orcid.org/0000-0003-0233-5739)
- Fan Yang (ORCID: https://orcid.org/0009-0008-3339-249X)
- Jing Du (ORCID: https://orcid.org/0009-0007-0350-2734)
Institutions
- Shanxi Medical University (CN)
- Shaanxi Provincial People's Hospital (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Tang Du Hospital (CN)
- Xijing Hospital (CN)
- Shanxi Provincial People’s Hospital (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-04-27
- DOI
- https://doi.org/10.1007/s00432-025-06210-0
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00