Pulsed laser deposition of hydroxyapatite coatings on laser sintered polyamide for enhanced osseointegration

This investigation endeavours to augment the surface characteristics of Laser-Sintered Polyamide (LSPo) through the application of a bioactive material , thereby enhancing cell-surface interaction. Hydroxyapatite (HA), a preeminent bioactive compound, is renowned for fostering osseous tissue anchorage, ensuring the enduring stability of implants. The HA bioactive coating was synthesized over LSPo (HA/LSPo) employing Pulsed Laser Deposition (PLD) across variable laser energy intensities to scrutinize the resultant properties of the fabricated layer. The process yielded solidified droplet particulates characterized by heterogeneous grain sizes and layer thicknesses ranging from 1.32 to 3.94 μm. Analytical techniques such as X-Ray Diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR) corroborated the presence of HA on the engineered surface. Preliminary cytocompatibility assessments indicate that HA/LSPo exhibits substantial biocompatibility, attributable to the synergistic influence of surface roughness and the hydrophobic nature of the layer. The findings substantiate the potential of HA/LSPo, fabricated via PLD, as high-caliber implant devices conducive to cellular adhesion, proliferation, and tissue regeneration . • HA coatings on polyamide were developed using pulsed laser deposition (PLD). • Laser energy modulates coating roughness, crystallinity, and hydrophobicity. • Surface contact angle increased from 86.2° to 138.9° with HA deposition. • Coatings at 130–140 mJ enhanced MG-63 cell adhesion and proliferation. • Structured HA layers improved hardness, Young's modulus, and bio integration.