Investigating the causal relationship between immune cells and colorectal cancer risk using bidirectional and multivariable Mendelian randomization analysis
These findings highlight specific immune cells' roles in CRC pathogenesis, suggesting potential avenues for immune-targeted therapies and CRC prevention. Given the rising global incidence of CRC, understanding immune cell roles is crucial for advancing effective treatments.
Authors
- Yeliu Liu (ORCID: https://orcid.org/0000-0003-0802-0674)
- Jiajie Zhou (ORCID: https://orcid.org/0000-0001-5886-7561)
Institutions
- Huaian First People’s Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Receptors and Signal Transduction
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1080/10799893.2025.2491068
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00