<i>Staphylococcus aureus</i> in Rwandan dogs predominantly representing human-associated lineages
The present study aimed at examining the nasal and ear carriage of Staphylococcus aureus of Rwandan dogs and cats. Sixty-five S. aureus isolates were detected, all originating from the nostrils of dogs. Resistance to penicillin, penicillin/erythromycin/clindamycin, penicillin/tetracycline, and tetracycline solely was observed. The isolates were assigned to 23 different spa types, among them three novel (t21589, t21661, and t21662) variants, associated with eleven clonal complexes (CCs) (CC1, CC5, CC12, CC15, CC22, CC30, CC45, CC97, CC152, CC707, and CC834). Four isolates could not be assigned to any known CC. MLST revealed that one of them belonged to the new sequence type (ST) 9069. Panton-Valentine leukocidin (PVL) genes (lukF-PV/lukS-PV), the bovine leukocidin genes (lukM/lukF-P83), the toxic shock syndrome toxin gene tst-1, and various virulence-associated genes were detected. These findings demonstrate the dogs are colonized with human lineages of S. aureus. Coupled with the limited availability of S. aureus data from human medicine in Rwanda underscores the importance of hygiene measures and supports the need for a rigorous One-Health Surveillance program of the companion animals-human interface.
Authors
- Adriana Cabal Rosel (ORCID: https://orcid.org/0000-0001-9346-1612)
- Stefan Monecke (ORCID: https://orcid.org/0000-0003-4368-8709)
- Štefan Schwarz (ORCID: https://orcid.org/0000-0002-6303-8212)
- Igor Loncaric (ORCID: https://orcid.org/0000-0003-1401-2961)
- Amélie Desvars-Larrive (ORCID: https://orcid.org/0000-0001-7671-696X)
- Tom Grunert (ORCID: https://orcid.org/0000-0001-5722-6631)
- Andrea T. Feßler (ORCID: https://orcid.org/0000-0002-0510-7347)
- Monika Ehling‐Schulz (ORCID: https://orcid.org/0000-0001-7384-0594)
- Joachim Spergser (ORCID: https://orcid.org/0000-0002-0164-0179)
- Frank Künzel
- Werner Ruppitsch (ORCID: https://orcid.org/0000-0001-9940-3333)
- Ralf Ehricht (ORCID: https://orcid.org/0000-0002-6612-0043)
- Michael P. Szostak (ORCID: https://orcid.org/0000-0002-3336-6434)
- Emmanuel Irimaso (ORCID: https://orcid.org/0000-0001-7805-0903)
- Elke Müller
- Sascha D. Braun
- L. Marek
- Otto W Fischer
- Jean Bosco Turikumwenayo
- Beatrice Mukamulisa
- Prudence Ndishimye
- Flora Muragijemariya
Institutions
- University of Veterinary Medicine Vienna (AT)
- Leibniz Institute of Photonic Technology (DE)
- University of Rwanda (RW)
- Complexity Science Hub (AT)
- Czech Academy of Sciences, Institute of Microbiology (CZ)
- Veterinary Medical Center (JP)
- InfectoGnostics Research Campus Jena (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- KVG Dental College & Hospital (IN)
- Austrian Agency for Health and Food Safety (AT)
- Freie Universität Berlin (DE)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Letters in Applied Microbiology
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1093/lambio/ovaf065
- Citations
- 1
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 1.40