Exploring the mediating role of plasma lipidome in the pathway from gut microbiota to dementia: A Mendelian randomization study
Our results suggest a link between the GM and the plasma lipidome with five distinct types of dementia, indicating that the phosphatidylcholine (O-16:1_18:2) level could play a role in the pathway from the species <i>Bacteroides coprocola</i> to vascular dementia.
Authors
- Weisen Wang
- Tianren Wang (ORCID: https://orcid.org/0000-0002-9761-8434)
- Xiaoying Bi (ORCID: https://orcid.org/0000-0001-5784-7294)
- Xiaoyan Sun (ORCID: https://orcid.org/0000-0001-7168-1358)
- Binghan Li
- Yuting Kan
- Cheng Wu
- Yongbo Hu
- Xiao Luo (ORCID: https://orcid.org/0009-0007-5246-915X)
Institutions
- Second Military Medical University (CN)
- Changhai Hospital (CN)
Publication Details
- Journal
- Archives of Medical Science
- Published
- 2025-04-26
- DOI
- https://doi.org/10.5114/aoms/201447
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China