Novel near-infrared 2H-chromene-based ratiometric fluorescent probe: Rapidly monitoring hydrazine in real samples

A novel near-infrared (NIR Ⅰ) fluorescent probe MCM-OMe with 2H-chromene scaffold was designed, synthesized and investigated it optical properties. MCM-OMe was identified as a novel hydrazine detector through nucleophilic substitution reaction with hydrazine, changing the color from red to blue. The emission spectra showed a clear intensity shift from MCM-OMe to its corresponding product MCH, indicating that MCM-OMe has ratiometric fluorescent property. Meanwhile, MCM-OMe exhibits acid-base tolerance with high selectivity and sensitivity to the residual N₂H₄. Moreover, the probe is equally suitable for the detection of residual hydrazine in water, soils and foods. Therefore, we provide a novel ratiometric fluorescent probe to detect hydrazine through a low-cost, easy-to-manufacture and easy-to-operate way.