Nasal epithelioid hemangioendothelioma - A rare case report and review of literature

To understand the complexities in diagnosing and managing a rare case of Nasal epithelioid hemangioendothelioma, which can be clinically misdiagnosed as benign inflammatory conditions. Epithelioid hemangioendothelioma (EHE) is a rare locally invasive vascular tumor and it is characterized by proliferation of endothelial cells with epithelioid morphology. It is slow growing tumor with borderline malignant potential and has high chances of recurrence. Mostly seen in soft tissues of extremities, lungs and very rarely seen in head and neck. There are very few cases reported of EHE in nasal cavity. The present case report describes an unusual case of EHE of nasal cavity in a 37 year old male with 2 months history of nasal mass, obstruction and intermittent epistaxis. Patient underwent wide local excision of tumor and histopathology confirmed the diagnosis. Usually wide local excision is the treatment of choice. Routinely regular follow up is advised. In cases of multiple recurrences and incompletely excised tumors radiation therapy is considered. It is an indolent tumor which has potential for recurrence that is known to appear during adult life and unlikely to metastasize. • Epithelioid Hemangioendothelioma (EHE) is a slow-growing tumor with borderline malignant potential. • Wide local excision with negative margins is the treatment of choice for nasal EHE. • Diagnosis confirmed with IHC markers CD31 and ERG, distinguishing EHE from other vascular tumors. • EHE exhibits high recurrence potential so, regular follow-up is necessary post-surgery. • Radiation therapy considered for recurrent or incompletely excised nasal EHE cases.