ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy
In summary, we provide mechanistic evidence for ER-phagy playing a hitherto unknown central role in the clinical synergy between HDACi and chemotherapy.
Authors
- Pierfrancesco Polo
- Frederik Helmprobst (ORCID: https://orcid.org/0000-0001-7704-2848)
- Matthias Lauth (ORCID: https://orcid.org/0000-0001-5922-5384)
- Alexander Visekruna (ORCID: https://orcid.org/0000-0002-5207-9545)
- Till Adhikary (ORCID: https://orcid.org/0000-0003-1951-5605)
- Thomas M. Gress (ORCID: https://orcid.org/0000-0002-9333-5461)
- Felix J Gössl
- André Menzenbach
Institutions
- Philipps University of Marburg (DE)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1186/s12964-025-02198-9
- Citations
- 1
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Philipps-Universität Marburg
- Deutsche Forschungsgemeinschaft