Single-cell transcriptomics reveals that human milk feeding shapes neonatal immune cell interleukin signaling pathways in a nonrandomized clinical trial
These findings suggest that human milk downregulates peripheral immune cell cytokine transcriptional signatures linked to allergic inflammation and infection relative to formula feeding.
Authors
- Robert S. Chapkin (ORCID: https://orcid.org/0000-0002-6515-3898)
- Sharon M. Donovan (ORCID: https://orcid.org/0000-0002-9785-4189)
- James J. Cai (ORCID: https://orcid.org/0000-0002-8081-6725)
- Michael L. Salinas (ORCID: https://orcid.org/0000-0001-5609-3996)
- Laurie A. Davidson (ORCID: https://orcid.org/0000-0002-4159-4680)
- Laxmi Yeruva (ORCID: https://orcid.org/0000-0003-4289-9109)
- Bharath Kumar Mulakala (ORCID: https://orcid.org/0000-0003-0527-5882)
Institutions
- Texas A&M University System (US)
- Urbana University (US)
- Arkansas Children's Nutrition Center (US)
- Arkansas Department of Agriculture (US)
- Texas A&M University (US)
Publication Details
- Journal
- American Journal of Clinical Nutrition
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1016/j.ajcnut.2025.04.024
- Citations
- 6
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 6.72