Study on the detection rate, genetic polymorphism, viral load, persistent infection capacity, and pathogenicity of human papillomavirus type 33
The E6 + E7 prototype has a significant impact on the pathogenicity and persistent infection capacity of HPV33. Viral load is positively correlated with pathogenicity and persistent infection capacity. It may serve as a biomarker for predicting disease progression during HPV33 screening. Other mechanisms underlying allele replacement require further investigation.
Authors
- Zhiqiang An (ORCID: https://orcid.org/0000-0001-9309-2335)
- Qiongyao Li
- G B Liu
- Di Tian (ORCID: https://orcid.org/0000-0002-8260-8575)
- Feng Yang (ORCID: https://orcid.org/0009-0002-9284-1431)
- Lei Li (ORCID: https://orcid.org/0000-0002-8828-5199)
- Yan Yang (ORCID: https://orcid.org/0000-0003-0887-2770)
- Qimin Cheng (ORCID: https://orcid.org/0000-0001-6713-7544)
- Mingjing Zhang (ORCID: https://orcid.org/0000-0003-4762-2344)
- Zuyi Chen (ORCID: https://orcid.org/0000-0001-8003-4478)
- A Peixin
Institutions
- Zunyi Medical University (CN)
- Chongqing Maternal and Child Health Hospital (CN)
- Affiliated Hospital of Zunyi Medical College (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1186/s12985-025-02752-4
- Citations
- 2
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guizhou Province