SHRs, biomarkers for dysregulated stress response, predict prognosis in sepsis patients: a retrospective cohort study from MIMIC-IV database
SHR serves as a robust marker of the dysregulated stress response in sepsis and holds significant prognostic value, particularly SHRmax, in predicting mortality. These findings underscore the potential clinical utility of SHR in guiding therapeutic strategies aimed at modulating the stress response and blood glucose levels in critically ill sepsis patients. Further research is warranted to explore SHR-targeted interventions in sepsis management.
Authors
- Xiaoting Wang (ORCID: https://orcid.org/0000-0001-6604-2834)
- Guangjian Wang (ORCID: https://orcid.org/0000-0001-5117-7218)
- Wei He (ORCID: https://orcid.org/0000-0002-3503-8530)
- Hongmin Zhang (ORCID: https://orcid.org/0000-0002-7514-3087)
- Hui Lian (ORCID: https://orcid.org/0000-0002-6542-9356)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1186/s12879-025-11011-4
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Peking Union Medical College Hospital