[MRI-guided high-intensity focused ultrasound treatment for movement disorders].

Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) therapy represents a novel, non-invasive, and non-surgical interventional approach for movement disorders, particularly essential tremor and Parkinson's disease. This technique creates an ablative thermal lesion at a target point with millimetric precision, disrupting specific dysfunctional neural circuits. In essential tremor, ventral intermediate nucleus thalamotomy using MRgHIFU leads to significant and lasting improvements in postural and kinetic tremor, ultimately enhancing patients' quality of life. Adverse effects of MRgHIFU are common, but they are mostly transient and mild in severity. This technology continues to improve and its indications continue to expand.

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Publication Details

Journal
PubMed
Published
2025-04-23
DOI
https://doi.org/10.53738/revmed.2025.21.915.47191
Primary Topic
Neurological disorders and treatments
Type
article
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article

[MRI-guided high-intensity focused ultrasound treatment for movement disorders].

Vanessa Fleury, Emilie Tomkova, Shahan Momjian, Sabina Catalano Chiuvé et al.
PubMed
Neurological disorders and treatments
article

[MRI-guided high-intensity focused ultrasound treatment for movement disorders].

Vanessa Fleury, Emilie Tomkova, Shahan Momjian, Sabina Catalano Chiuvé, Orane Lorton, Alma Lingenberg, Christo Bratanov
article en

Abstract

Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) therapy represents a novel, non-invasive, and non-surgical interventional approach for movement disorders, particularly essential tremor and Parkinson's disease. This technique creates an ablative thermal lesion at a target point with millimetric precision, disrupting specific dysfunctional neural circuits. In essential tremor, ventral intermediate nucleus thalamotomy using MRgHIFU leads to significant and lasting improvements in postural and kinetic tremor, ultimately enhancing patients' quality of life. Adverse effects of MRgHIFU are common, but they are mostly transient and mild in severity. This technology continues to improve and its indications continue to expand.

PubMedVol. 21(915)
University of Geneva (CH), Hôpital Beau-Séjour (CH)
Neurological disorders and treatments
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