The LncRNA RMST-miR-4295-ITPR1 axis: a key mechanism in regulating autophagy in triple-negative breast cancer cells
Our findings indicate that the LncRNA RMST-miR-4295-ITPR1 axis plays a crucial role in regulating autophagy in TNBC cells. The modulation of this axis may represent a novel therapeutic strategy for inhibiting TNBC progression and overcoming chemoresistance.
Authors
- Hao Guo (ORCID: https://orcid.org/0000-0002-5091-5757)
- Linlei Zhang (ORCID: https://orcid.org/0000-0001-8828-8341)
- Sainan Li (ORCID: https://orcid.org/0000-0002-1880-6294)
- Bo Wang (ORCID: https://orcid.org/0000-0002-9620-3413)
- Cuizhi Geng (ORCID: https://orcid.org/0000-0001-5541-5412)
- Jiajie Shi (ORCID: https://orcid.org/0000-0002-6118-4742)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1186/s12885-025-14189-7
- Citations
- 5
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 4.68