Pan-genome analysis of the Enterobacter hormaechei complex highlights its genomic flexibility and pertinence as a multidrug resistant pathogen

This study addressed key issues pertaining to the taxonomy of the E. hormaechei complex, which may contribute towards more accurate identification of strains belonging to this species complex in the clinical setting. The pathogenicity determinants identified in this study could serve as a basis for a deeper understanding of E. hormaechei complex pathogenesis and virulence. The extensive nature of multidrug resistance among E. hormaechei complex strains highlights the need for responsible antibiotic stewardship to ensure effective treatment of these emerging pathogens.

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Publication Details

Journal
BMC Genomics
Published
2025-04-26
DOI
https://doi.org/10.1186/s12864-025-11590-1
Citations
7
Primary Topic
Enterobacteriaceae and Cronobacter Research
Type
article
Field-Weighted Citation Impact
12.59

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article

Pan-genome analysis of the Enterobacter hormaechei complex highlights its genomic flexibility and pertinence as a multidrug resistant pathogen

Teresa A. Coutinho, Pieter De Maayer, Theo H. M. Smits, T.L. Green et al.
7 citations
BMC Genomics
Enterobacteriaceae and Cronobacter Research
12.59
article

Pan-genome analysis of the Enterobacter hormaechei complex highlights its genomic flexibility and pertinence as a multidrug resistant pathogen

Teresa A. Coutinho, Pieter De Maayer, Theo H. M. Smits, T.L. Green, Sara Jordan
article en
7 citations

Abstract

This study addressed key issues pertaining to the taxonomy of the E. hormaechei complex, which may contribute towards more accurate identification of strains belonging to this species complex in the clinical setting. The pathogenicity determinants identified in this study could serve as a basis for a deeper understanding of E. hormaechei complex pathogenesis and virulence. The extensive nature of multidrug resistance among E. hormaechei complex strains highlights the need for responsible antibiotic stewardship to ensure effective treatment of these emerging pathogens.

BMC GenomicsVol. 26(1)
University of the Witwatersrand (ZA), ZHAW Zurich University of Applied Sciences (CH), University of Pretoria (ZA), ZHAW Zurich University of Applied Sciences (CH)
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Life in Land
Openalex Percentile: Top 1%
Enterobacteriaceae and Cronobacter Research
12.59
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