Pan-genome analysis of the Enterobacter hormaechei complex highlights its genomic flexibility and pertinence as a multidrug resistant pathogen
This study addressed key issues pertaining to the taxonomy of the E. hormaechei complex, which may contribute towards more accurate identification of strains belonging to this species complex in the clinical setting. The pathogenicity determinants identified in this study could serve as a basis for a deeper understanding of E. hormaechei complex pathogenesis and virulence. The extensive nature of multidrug resistance among E. hormaechei complex strains highlights the need for responsible antibiotic stewardship to ensure effective treatment of these emerging pathogens.
Authors
- Teresa A. Coutinho (ORCID: https://orcid.org/0000-0002-3227-4343)
- Pieter De Maayer (ORCID: https://orcid.org/0000-0001-8550-642X)
- Theo H. M. Smits (ORCID: https://orcid.org/0000-0002-1237-235X)
- T.L. Green (ORCID: https://orcid.org/0009-0003-6502-9891)
- Sara Jordan
Institutions
- University of the Witwatersrand (ZA)
- ZHAW Zurich University of Applied Sciences (CH)
- University of Pretoria (ZA)
- ZHAW Zurich University of Applied Sciences (CH)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1186/s12864-025-11590-1
- Citations
- 7
- Primary Topic
- Enterobacteriaceae and Cronobacter Research
- Type
- article
- Field-Weighted Citation Impact
- 12.59
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung