Pharmacometabolomics Detects Various Unreported Metoprolol Metabolites in Urine of (Potential) Living Kidney Donors and Kidney Transplant Recipients
We found more metoprolol metabolites than previously reported, calling for replication studies and evaluation of pharmacogenetic testing approaches to realize safer, more effective metoprolol therapy.
Authors
- Marieke A. J. Hof (ORCID: https://orcid.org/0000-0002-5769-1522)
- Frank Klont (ORCID: https://orcid.org/0000-0003-3503-1694)
- Gérard Hopfgartner (ORCID: https://orcid.org/0000-0002-9087-606X)
- Piotr Sosnowski (ORCID: https://orcid.org/0000-0003-4261-269X)
- Stephan J. L. Bakker
- Wietske A Heddema
Institutions
- University of Geneva (CH)
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- University of Warsaw (PL)
Publication Details
- Journal
- Clinical Pharmacokinetics
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1007/s40262-025-01502-7
- Citations
- 3
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 4.67
Funders
- Stichting voor de Technische Wetenschappen