Pathological and Molecular Studies of <i>Neospora caninum</i> Infection in Aborted Bovine Foetuses in Khorasan Razavi Province, Iran
In the present study, N. caninum infection was detected in 24.76% (26 out of 105) of aborted bovine foetuses by nested PCR analysis. The brain tissues of 20 bovine-aborted foetuses were only suitable for histopathological examination. Lesions of the central nervous system were severe hyperaemia, perivascular cuffing, astrogliosis, mild encephalitis and focal necrosis. One foetus exhibited a 32-µm N. caninum cyst within the brain tissue. IgG antibodies against N. caninum were identified in all dairy cattle that aborted infected foetuses through ELISA testing. Molecular, histopathological and serological findings strongly suggest that N. caninum plays a significant role in bovine abortion in dairy cattle in Khorasan Razavi Province, northeast Iran.
Authors
- Asma Keyvanlou Shahrestanaki (ORCID: https://orcid.org/0009-0006-6265-4837)
- Hossein Nourani (ORCID: https://orcid.org/0000-0002-4035-1118)
- Gholam Reza Razmi (ORCID: https://orcid.org/0000-0002-0754-1278)
Institutions
- Ferdowsi University of Mashhad (IR)
Publication Details
- Journal
- Veterinary Medicine and Science
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1002/vms3.70329
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ferdowsi University of Mashhad