Identification for Immunogenic Epitopes Candidates of CD16A Mimetics

CD16 A is a transmembrane protein with a short C-ter cytoplasmic tail and possesses two extracellular Iglike domains. CD16A displays ADCC potent killing effect competing with tumors and virus. For obtaining highly specific targeting CD16A antibodies, designing CD16A antigen appears to be particularly necessary so that enhancing combination between CD16A and anti-CD16A antibody and effectively recognizing CD16A binding sites.