Outcomes of Heart Failure Patients on Palliative Inotrope Therapy in the Hospice Setting: A Single Center Retrospective Cohort Study

<b><i>Background:</i></b> Chronic intravenous inotropic support (CIIS) is recommended as palliative therapy for end-stage heart failure (HF) but is underutilized in hospice settings. <b><i>Objectives:</i></b> This study evaluates outcomes for patients on CIIS receiving hospice care. <b><i>Design:</i></b> Retrospective cohort study using electronic health records of patients on CIIS admitted to hospice. <b><i>Setting/Subjects:</i></b> Twenty-one patients admitted to a mid-Atlantic hospice between 2018 and 2022. <b><i>Measurements:</i></b> Data collected included demographics, inotropic therapy details, hospice length of stay (LOS), hospitalizations, and medication usage. <b><i>Results:</i></b> The mean age was 72.9 years; 67% were on milrinone. Patients had a mean hospice LOS of 49.6 days, with 66% experiencing no hospitalizations. Only 24% of patients required high-dose opioids. 24% of patients were discharged alive from hospice, and 52% died at home. <b><i>Conclusion:</i></b> Caring for patients on CIIS in hospice appears feasible and may portend some benefits to patients. Further research is warranted to confirm these findings in a prospective observational cohort.

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Publication Details

Journal
Journal of Palliative Medicine
Published
2025-04-26
DOI
https://doi.org/10.1089/jpm.2024.0492
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Outcomes of Heart Failure Patients on Palliative Inotrope Therapy in the Hospice Setting: A Single Center Retrospective Cohort Study

Hunter Groninger, Farooq H. Sheikh, Kelley M. Anderson, Umer Arif Esbhani et al.
Journal of Palliative Medicine
Heart Failure Treatment and Management
article

Outcomes of Heart Failure Patients on Palliative Inotrope Therapy in the Hospice Setting: A Single Center Retrospective Cohort Study

Hunter Groninger, Farooq H. Sheikh, Kelley M. Anderson, Umer Arif Esbhani, Eric G Bush, Candice Tavares, Anirudh Rao, Syed Muhammad Ali Abidi
article en

Abstract

<b><i>Background:</i></b> Chronic intravenous inotropic support (CIIS) is recommended as palliative therapy for end-stage heart failure (HF) but is underutilized in hospice settings. <b><i>Objectives:</i></b> This study evaluates outcomes for patients on CIIS receiving hospice care. <b><i>Design:</i></b> Retrospective cohort study using electronic health records of patients on CIIS admitted to hospice. <b><i>Setting/Subjects:</i></b> Twenty-one patients admitted to a mid-Atlantic hospice between 2018 and 2022. <b><i>Measurements:</i></b> Data collected included demographics, inotropic therapy details, hospice length of stay (LOS), hospitalizations, and medication usage. <b><i>Results:</i></b> The mean age was 72.9 years; 67% were on milrinone. Patients had a mean hospice LOS of 49.6 days, with 66% experiencing no hospitalizations. Only 24% of patients required high-dose opioids. 24% of patients were discharged alive from hospice, and 52% died at home. <b><i>Conclusion:</i></b> Caring for patients on CIIS in hospice appears feasible and may portend some benefits to patients. Further research is warranted to confirm these findings in a prospective observational cohort.

Journal of Palliative MedicineVol. 28(10)
MedStar Washington Hospital Center (US), Georgetown University (US), Chesapeake College (US), University of Maryland Upper Chesapeake Health (US), MedStar Heart & Vascular Institute (US), University of Virginia (US)
Good health and well-being
Openalex Percentile: Top 84%
Heart Failure Treatment and Management
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