Tanshinone IIA alleviates tri-ortho-cresyl phosphate-induced ovarian damage through Hippo signaling pathway activation in mice
Tanshinone IIA alleviates TOCP-induced ovarian dysfunction primarily through coordinated modulation of Hippo signaling and AKT/MAPK pathway activities, offering a potential therapeutic strategy for chemical-induced ovarian injury.
Authors
- Tao Luo (ORCID: https://orcid.org/0000-0001-7146-6121)
- Chong Zhou (ORCID: https://orcid.org/0000-0002-9630-8223)
- Liping Zheng (ORCID: https://orcid.org/0000-0001-6102-2332)
- Liaoliao Hu
- Wencan Wang (ORCID: https://orcid.org/0000-0002-8849-9090)
- Yue Xue (ORCID: https://orcid.org/0009-0004-2141-2044)
- Xiu Cheng
- Na Hu (ORCID: https://orcid.org/0000-0002-5916-0143)
- Jianlin Yu (ORCID: https://orcid.org/0009-0006-7553-9459)
- Zhangqiang Ma (ORCID: https://orcid.org/0000-0003-1776-3525)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1186/s13048-025-01671-w
- Citations
- 1
- Primary Topic
- Phytochemical and Pharmacological Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- National Natural Science Foundation of China