A Novel Approach to Gastrointestinal Bleeding Risk Stratification and Proton Pump Inhibitor Effectiveness in Patients with Acute Coronary Syndrome on Dual Antiplatelet Therapy: A Nationwide Retrospective Cohort Study
The mARC-HBR criteria enhance the identification of high GI bleeding risk patients with ACS and may inform targeted PPI use, given the observed associations suggesting potential benefit in high-risk ticagrelor users and limited effect in low-risk groups.
Authors
- Kyu‐Nam Heo (ORCID: https://orcid.org/0000-0003-3626-3999)
- Jaekyu Shin (ORCID: https://orcid.org/0000-0002-7097-9977)
- Ju‐Yeun Lee (ORCID: https://orcid.org/0000-0002-2261-7330)
- Mee Yeon Lee
Institutions
- Seoul National University (KR)
- University of California, San Francisco (US)
- University of California System (US)
Publication Details
- Journal
- Cardiovascular Drugs and Therapy
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1007/s10557-025-07702-4
- Citations
- 1
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Research Foundation
- Seoul National University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea