Immune-related gene expression with colorectal cancer risk: a Mendelian randomization analysis
Our study provides a novel perspective on the potential causal link between the low expression of FHL3 gene and the risk of CRC. More evidence is essential to further reveal the biological mechanisms underlying this association.
Authors
- Weihao Yang (ORCID: https://orcid.org/0000-0002-4568-4640)
- Heng‐Yi Zhang (ORCID: https://orcid.org/0009-0001-7735-7759)
- Jianguang Ji (ORCID: https://orcid.org/0000-0003-0324-9496)
- Zhenzhan Zhang (ORCID: https://orcid.org/0000-0001-7686-8082)
- Donghua Huang
- Yangyang Luo (ORCID: https://orcid.org/0000-0003-3441-6621)
- Wenjun He (ORCID: https://orcid.org/0000-0003-1307-3455)
- Tao Chen (ORCID: https://orcid.org/0000-0001-9527-1142)
- Hao Liu (ORCID: https://orcid.org/0000-0002-3625-0437)
- Xin Tan (ORCID: https://orcid.org/0000-0003-3785-9700)
- Mengting Lu
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1007/s12672-025-02291-y
- Citations
- 2
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- United Mitochondrial Disease Foundation
- Natural Science Foundation of Guangdong Province
- Universidade de Macau
- Southern Medical University
- Nanfang Hospital
- Higher Education Discipline Innovation Project