Fluoroquinolones and the risk of aortic aneurysm or dissection: A population‐based propensity score‐matched German cohort study
In a German cohort study, FQ use was associated with a 52% increased risk for aortic aneurysm or dissection within 60 days compared with macrolide use. The risk of FQ-associated aortic aneurysm or dissection compared to macrolides can be replicated in German routine health care data. Extending the analysis, we provided new insights that the effect size may depend on the chosen AC.
Authors
- Julia Wicherski (ORCID: https://orcid.org/0000-0001-9630-6239)
- Katrin Schuessel (ORCID: https://orcid.org/0000-0002-8377-2254)
- Britta Haenisch (ORCID: https://orcid.org/0000-0002-4828-6058)
- Gabriela Brückner
- Cornelia Becker (ORCID: https://orcid.org/0000-0003-4161-4407)
- Andreas Schlotmann
- H. Schröder (ORCID: https://orcid.org/0009-0008-1447-6794)
- Winfried V. Kern (ORCID: https://orcid.org/0000-0003-2550-358X)
- Jonas Peltner (ORCID: https://orcid.org/0000-0002-1682-7913)
Institutions
- Federal Institute for Drugs and Medical Devices (DE)
- University of Bonn (DE)
- University of Freiburg (DE)
- German Center for Neurodegenerative Diseases (DE)
- Wissenschaftliches Institut der AOK (DE)
Publication Details
- Journal
- Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1002/phar.70020
- Citations
- 1
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 1.26