Human umbilical cord mesenchymal stem cell-derived exosomal miR-455-3p targets CAMK2N1 to improve trophoblast cell injury in gestational diabetes mellitus
miR-455-3p derived from hucMSCs-Exos exerts a protective effect against trophoblast cell injury in GDM by targeting and downregulating CAMK2N1.
Authors
- Jinman Zhang
- Baosheng Zhu (ORCID: https://orcid.org/0000-0002-5991-1752)
- Runmei Ma
- Mingyu Du
- Yan Zhang (ORCID: https://orcid.org/0000-0002-4835-8541)
Institutions
- Kunming Medical University (CN)
- National Health and Family Planning Commission (CN)
- National Center on Birth Defects and Developmental Disabilities (US)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1186/s13098-025-01692-x
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Kunming Medical University