The Burden of Post-Transplant Malignancies: Four Illustrative Cases of Diverse Etiologies

However, immunosuppression, which affects T cell activity, immunosurveillance, and the immunological management of oncogenic viral infections, is responsible for the increased risk of post-renal transplant malignancies [2].It is the third most common cause of mortality in kidney transplant recipients, after infections and cardiovascular mortality.The overall incidence of malignancies is much higher than in the general population as well as patients on maintenance haemodialysis [3].Post-transplant malignancies usually develop de novo, by donor-related transmission, or by recurrence of patient's pre-transplant malignancy [4].Here we present 4 cases of post renal transplant malignancies with varied aetiologies.