Does ankylosing spondylitis exert a bidirectional influence on hypertension? A two-sample Mendelian randomization study
This study represents the first two-sample Mendelian randomization analysis aimed at investigating the causal genetic relationship between ankylosing spondylitis and blood pressure. Our Mendelian randomization analysis results revealed a lack of causal association between ankylosing spondylitis and hypertension, diastolic blood pressure, as well as systolic blood pressure.
Authors
- Yanzheng Gao (ORCID: https://orcid.org/0000-0002-2937-815X)
- Guang Yang (ORCID: https://orcid.org/0000-0002-1379-0684)
- Weiran Hu (ORCID: https://orcid.org/0000-0001-7924-7820)
- Haoxu Wang (ORCID: https://orcid.org/0009-0001-7876-3417)
- Kai Zhang (ORCID: https://orcid.org/0000-0001-8581-9063)
Institutions
- Henan University (CN)
- Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
- Zhengzhou People's Hospital (CN)
Publication Details
- Journal
- SAGE Open Medicine
- Published
- 2025-04-26
- DOI
- https://doi.org/10.1177/20503121251335513
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00