Exploring the Causal Relationship Between Gut Microbiota and Inflammatory Bowel Disease Using Two-Sample Mendelian Randomization, and Bayesian Weighted Validation

Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease of the gastrointestinal tract, the main types of which include Ulcerative colitis (UC) and Crohn’s disease (CD) [1,2]. It has been reported that nearly 3.9 million females and nearly 3 million males are currently suffering from IBD globally and the number of cases is rising.