Prefrontal cortex activation during daily movements and its association with clinical symptoms in knee osteoarthritis
People with knee OA utilized greater executive control during step-up compared to walking. Similar to stair climbing, step-up is more physically demanding and more frequently impaired than walking. Greater pain catastrophizing was related to smaller increases in PFC activation from walking to step-up, reflecting the availability of fewer executive resources to maintain task performance.
Authors
- Deepak Kumar (ORCID: https://orcid.org/0000-0003-1728-484X)
- Meryem A. Yücel (ORCID: https://orcid.org/0000-0002-4291-2847)
- Soyoung Lee (ORCID: https://orcid.org/0000-0002-6651-179X)
- Claudio L. Ferre (ORCID: https://orcid.org/0000-0002-4370-6965)
- Baekdong Cha (ORCID: https://orcid.org/0000-0003-0313-4998)
- Ehyun Kim
Institutions
- Boston University (US)
Publication Details
- Journal
- Osteoarthritis and Cartilage Open
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1016/j.ocarto.2025.100615
- Citations
- 1
- Primary Topic
- Musculoskeletal pain and rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Rheumatology Research Foundation
- Boston University
- International Society of Biomechanics
- National Institutes of Health