Alpha thalassemia trait in a child with juvenile diabetes: a case report

Alpha thalassemia trait (two missing α-globin genes) manifests as a microcytic anaemia that can be mistaken for iron-deficiency anaemia. A 12‑year‑old female child, who is a known case of type 1 diabetes mellitus presented with persistent microcytic hypochromic anaemia which failed to improve even after iron therapy. She was evaluated for her low haemoglobin values with the peripheral smear showing microcytic hypochromic anaemia which eventually was diagnosed as alpha thalassemia trait. This case reiterates the association between a metabolic disorder and a haemoglobinopathy, which is rarely reported in children.

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Publication Details

Journal
International Journal of Contemporary Pediatrics
Published
2025-04-24
DOI
https://doi.org/10.18203/2349-3291.ijcp20251109
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Alpha thalassemia trait in a child with juvenile diabetes: a case report

Carol Sara Cherian, Bincy Philip, Manaal Kunnummal
International Journal of Contemporary Pediatrics
Hemoglobinopathies and Related Disorders
article

Alpha thalassemia trait in a child with juvenile diabetes: a case report

Carol Sara Cherian, Bincy Philip, Manaal Kunnummal
article en

Abstract

Alpha thalassemia trait (two missing α-globin genes) manifests as a microcytic anaemia that can be mistaken for iron-deficiency anaemia. A 12‑year‑old female child, who is a known case of type 1 diabetes mellitus presented with persistent microcytic hypochromic anaemia which failed to improve even after iron therapy. She was evaluated for her low haemoglobin values with the peripheral smear showing microcytic hypochromic anaemia which eventually was diagnosed as alpha thalassemia trait. This case reiterates the association between a metabolic disorder and a haemoglobinopathy, which is rarely reported in children.

International Journal of Contemporary PediatricsVol. 12(5)
Pushpagiri Medical College (IN)
Openalex Percentile: Top 87%
Hemoglobinopathies and Related Disorders
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