Early potential metabolic biomarkers of T1 stage lung adenocarcinoma based on serum metabolomics
Cortisol,3-Oxo-OPC4-CoA,PE-NMe(14:1(9Z)/14:1(9Z)), and Ceramide (d18:1/9Z-18:1) exhibit significantly altered metabolic levels in T1 stage lung adenocarcinoma patients and can serve as metabolic biomarkers. These markers may enhance the sensitivity and specificity of early diagnosis, facilitating improved detection of T1 stage lung adenocarcinoma.
Authors
- Bin Wu (ORCID: https://orcid.org/0000-0003-0413-6987)
- Ye Xu (ORCID: https://orcid.org/0000-0002-5520-3839)
- Min Zheng (ORCID: https://orcid.org/0000-0001-9148-7544)
- Ning Wang (ORCID: https://orcid.org/0000-0001-5287-5755)
- Wen Zhao (ORCID: https://orcid.org/0000-0003-3507-4264)
- Chen Ying Zhu (ORCID: https://orcid.org/0000-0002-4079-6491)
- Qingkui Guo
Institutions
- Tongren Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-04-25
- DOI
- https://doi.org/10.3389/fmolb.2025.1544774
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00