The mechanistic study of codonopsis pilosula on laryngeal squamous cell carcinoma based on network pharmacology and experimental validation
Codonopsis pilosula exerts antitumor effects in LSCC through the regulation of MAPK3 and multiple signaling pathways, providing a theoretical basis for its clinical application.
Authors
- Zhongxun Li (ORCID: https://orcid.org/0000-0001-5692-3697)
- Yi-Han Lou
- Yujia Guo (ORCID: https://orcid.org/0000-0002-2009-2286)
- Xiaofang Hou (ORCID: https://orcid.org/0000-0002-8558-4521)
- Huina Guo
- Xiaoya Guan (ORCID: https://orcid.org/0000-0002-2621-5283)
- Xuting Xue (ORCID: https://orcid.org/0000-0002-0654-3263)
- Ying Wang (ORCID: https://orcid.org/0009-0009-1519-4454)
- Qi Han (ORCID: https://orcid.org/0000-0002-6938-0342)
- Chunming Zhang (ORCID: https://orcid.org/0000-0001-7871-6170)
- Long He (ORCID: https://orcid.org/0000-0002-2814-6541)
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-25
- DOI
- https://doi.org/10.3389/fphar.2025.1542116
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00