Overexpression of MMP14 is associated with poor prognosis and immune cell infiltration in colon cancer
MMP14 plays a crucial role in CRC progression. Its overexpression is related to poor prognosis and immune cell infiltration. The prognostic model based on MMP14 co-expression genes may help predict CRC prognosis. However, further studies are needed to validate these findings, such as more <i>in-vitro</i> and <i>in-vivo</i> experiments. In conclusion, MMP14 can serve as a biomarker for evaluating CRC prognosis and immune cell infiltration.
Authors
- Nan Zhang (ORCID: https://orcid.org/0000-0001-6518-2501)
- Na Li (ORCID: https://orcid.org/0009-0001-8624-0114)
- Guanghui Wang (ORCID: https://orcid.org/0000-0001-8551-6468)
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- First Hospital of Xi'an (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-04-25
- DOI
- https://doi.org/10.3389/fonc.2025.1564375
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00