Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat
Berotralstat was consistently associated with a reduced risk of DDIs compared with Danazol. A rational assessment of DDIs would help select the best prophylactic treatment for HAE.
Authors
- Caterina Colangelo
- Paola Triggianese (ORCID: https://orcid.org/0000-0002-1954-2825)
- Valentina Popescu Janu
- Paolo Borrelli (ORCID: https://orcid.org/0009-0006-7966-5225)
- Emanuele Bizzi (ORCID: https://orcid.org/0000-0001-8560-5866)
- Tiziana De Pasquale
- Chiara Cogliati (ORCID: https://orcid.org/0000-0003-2980-6158)
- Francesco Ruben Giardino (ORCID: https://orcid.org/0000-0003-3293-8936)
- Massimo Triggiani (ORCID: https://orcid.org/0000-0001-7318-2093)
- Mauro Cancian (ORCID: https://orcid.org/0000-0003-2246-9144)
- Francesco Arcoleo (ORCID: https://orcid.org/0000-0002-7153-4208)
- Davide Firinu (ORCID: https://orcid.org/0000-0002-5768-391X)
- Donatella Bignardi (ORCID: https://orcid.org/0000-0001-9995-7467)
- Stefano Agolini
- Francesca Perego (ORCID: https://orcid.org/0000-0003-3973-6931)
- Riccardo Senter (ORCID: https://orcid.org/0000-0001-7987-8235)
- Antonio Gidaro (ORCID: https://orcid.org/0000-0002-5379-1091)
- Andrea Zanichelli (ORCID: https://orcid.org/0000-0002-7512-4644)
- P Accardo
- Vincenzo Montinaro (ORCID: https://orcid.org/0000-0003-4018-0221)
- Luisa Brussino (ORCID: https://orcid.org/0000-0001-7249-7616)
- Dario Cattaneo (ORCID: https://orcid.org/0000-0003-1512-6530)
- Paolina Quattrocchi
- Giuseppe Spadaro (ORCID: https://orcid.org/0000-0001-7889-425X)
- Oliviero Rossi
- Maria Domenica Guarino
Institutions
- University of Messina (IT)
- University of Rome Tor Vergata (IT)
- University of Salerno (IT)
- University of Padua (IT)
- University of Cagliari (IT)
- University of Milan (IT)
- Luigi Sacco Hospital (IT)
- Istituti Clinici Scientifici Maugeri (IT)
- L'organizzazione Ospedale di Civitanova M (IT)
- Ospedale Vincenzo Cervello (IT)
- IRCCS Policlinico San Donato (IT)
- Ospedali Riuniti di Ancona (IT)
- Azienda Ospedaliero Universitaria Ospedali Riuniti (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Ospedale Policlinico San Martino (IT)
- Azienda USL di Pescara (IT)
- ASST Fatebenefratelli Sacco (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-25
- DOI
- https://doi.org/10.3389/fphar.2025.1550133
- Citations
- 1
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 1.63