Impact of fatigue in Crohn's disease is negatively related to resting state functional connectivity between the superior parietal lobule and parahippocampal gyrus/hippocampus
In people with Crohn's disease, fatigue increases as functional connectivity between brain regions involved in sensorimotor integration and memory processing decreases.
Authors
- Jennifer Kornelsen (ORCID: https://orcid.org/0000-0003-0658-5321)
- Chase R. Figley (ORCID: https://orcid.org/0000-0001-6573-461X)
- Çharles N. Bernstein (ORCID: https://orcid.org/0000-0001-8041-3574)
- Md Nasir Uddin (ORCID: https://orcid.org/0000-0002-5887-1322)
- Ronak Patel (ORCID: https://orcid.org/0000-0003-0117-9041)
- John D. Fisk (ORCID: https://orcid.org/0000-0003-3512-8015)
- Erin L. Mazerolle (ORCID: https://orcid.org/0000-0002-2012-8605)
- Lesley A. Graff (ORCID: https://orcid.org/0000-0002-0743-3189)
- Theresa A. McIver
- Ruth Ann Marrie (ORCID: https://orcid.org/0000-0002-1855-5595)
Institutions
- Dalhousie University (CA)
- St. Francis Xavier University (CA)
- Health Sciences Centre (CA)
- University of Manitoba (CA)
- University of Rochester (US)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2025-04-25
- DOI
- https://doi.org/10.3389/fnhum.2025.1561421
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research Manitoba
- Crohn's and Colitis Canada
- Canadian Institutes of Health Research