Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders
Postprandial BAT activation is regulated by brain-derived UGN, which could serve as a novel therapeutic approach to enhance BAT activity in patients with obesity and T2D to improve postprandial glucose regulation.
Authors
- Pero Bubalo
- Aleksandra Dugandžić (ORCID: https://orcid.org/0000-0001-9454-7207)
- Milan Kordić
- Martina Ratko
- Spomenka Ljubić (ORCID: https://orcid.org/0000-0002-9631-3890)
- Martina Tkalčić
- Ivan Banovac (ORCID: https://orcid.org/0000-0001-8233-7405)
- Dora Sedmak (ORCID: https://orcid.org/0000-0001-9910-1781)
- Nikola Habek (ORCID: https://orcid.org/0000-0002-7774-7386)
- Petar Škavić (ORCID: https://orcid.org/0000-0002-0956-0624)
- Vladiana Crljen
- Siniša Škokić (ORCID: https://orcid.org/0000-0002-9065-9129)
- Marina Dobrivojević Radmilović (ORCID: https://orcid.org/0000-0002-2513-1889)
- Dario Rahelić (ORCID: https://orcid.org/0000-0002-2901-0646)
- Anton Mažuranić (ORCID: https://orcid.org/0000-0002-9353-5949)
Institutions
- University of Zagreb (HR)
- Klinička bolnica Merkur (HR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-25
- DOI
- https://doi.org/10.3389/fphar.2025.1569163
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Medicinski Fakultet, Sveučilište u Zagrebu