Thrombotic adverse events associated with TNF-alpha blockers: a real-world pharmacovigilance analysis of the FAERS database

This study suggests that TNF - α blockers are associated with various adverse events of thrombosis, with different risks in different patient groups and treatment stages. Clinical doctors should assess individual thrombosis risk and closely monitor coagulation related indicators when using TNF - α inhibitors. This study offers valuable insights for optimizing treatment and improving safety.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-04-25
DOI
https://doi.org/10.3389/fphar.2025.1512806
Citations
2
Primary Topic
Heparin-Induced Thrombocytopenia and Thrombosis
Type
article
Field-Weighted Citation Impact
4.01
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article

Thrombotic adverse events associated with TNF-alpha blockers: a real-world pharmacovigilance analysis of the FAERS database

Jingkai Di, Lijuan Song, Nan Yang, Xinglong Xing et al.
2 citations
Frontiers in Pharmacology
Heparin-Induced Thrombocytopenia and Thrombosis
4.01
article

Thrombotic adverse events associated with TNF-alpha blockers: a real-world pharmacovigilance analysis of the FAERS database

Jingkai Di, Lijuan Song, Nan Yang, Xinglong Xing, Yicong Zhao
article en
2 citations

Abstract

This study suggests that TNF - α blockers are associated with various adverse events of thrombosis, with different risks in different patient groups and treatment stages. Clinical doctors should assess individual thrombosis risk and closely monitor coagulation related indicators when using TNF - α inhibitors. This study offers valuable insights for optimizing treatment and improving safety.

Frontiers in PharmacologyVol. 16
Shanxi Medical University (CN), Second Hospital of Shanxi Medical University (CN), Shanxi Academy of Medical Sciences (CN)
Good health and well-being
Openalex Percentile: Top 8%
Heparin-Induced Thrombocytopenia and Thrombosis
4.01
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