Construction of Nickel Hydroxide Based Electrode Material and Its Performance for Non-enzymatic Glucose Sensing Applications

Abstract Conventional nanomaterials are used in electrochemical glucose non-enzymatic sensing, but their widespread application is restricted by high costs and complex preparation procedures. This study explores the use of nickel hydroxide (Ni(OH) 2 ), which was deposited onto the entire surface of a screen-printed gold electrode (SPGE) through one-step electrodeposition process, serving as an interface material for non-enzymatic glucose sensing. The surface morphology, composition and electrochemical properties of SPGE/Ni(OH) 2 were investigated using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), elemental mapping, cyclic voltammetry (CV) and chronoamperometry (CA). CV and CA results revealed that SPGE/Ni(OH) 2 exhibited excellent electrocatalytic activity towards glucose. The oxidation current was directly proportional to glucose concentrations ranging from 10 µM to 200 µM. Furthermore, the glucose sensor demonstrated a low detection limit of 1.8 µM in a basic solution and exhibited excellent selectivity. With its facile preparation and reliable performance, this sensor is a promising candidate for the next generation non-enzymatic glucose diagnostic devices.