Intrahepatic cholestasis of pregnancy and coagulation: a dual risk of hypercoagulability and bleeding

In ICP patients, hypercoagulability is a clinically significant concern that should be considered alongside bleeding risk. In our study, no significant differences were observed in routine coagulation tests, suggesting that more sensitive coagulation markers should be evaluated in ICP patients. The high rate of fetal complications indicates that early diagnosis, careful monitoring, and the implementation of individualized management plans are essential for the prevention of hematological and perinatal complications in pregnant women with intrahepatic cholestasis.