Meat and fish consumption, genetic risk and risk of severe metabolic-associated fatty liver disease: a prospective cohort of 487,875 individuals
High consumption of red and processed meat was associated with an increased risk of severe MAFLD, while oily fish intake showed an inverse association with the risk of MAFLD. These effects were consistent across genetic risk levels for MAFLD. Our findings reinforce dietary recommendations to limit red and processed meat and encourage oily fish intake for MAFLD prevention, irrespective of individual genetic risk.
Authors
- Jianjin Wang (ORCID: https://orcid.org/0000-0002-3416-3399)
- J. Mo (ORCID: https://orcid.org/0009-0001-4806-3129)
- Xuzhi Wan (ORCID: https://orcid.org/0000-0001-7362-9553)
- Yilei Fan (ORCID: https://orcid.org/0000-0001-6369-460X)
- Pan Zhuang
Institutions
- Shaoxing University (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Yuxian People's Hospital (CN)
Publication Details
- Journal
- Nutrition Journal
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1186/s12937-025-01134-4
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- China Association for Science and Technology
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province