Advancements in Herbal Drug Loaded Nanoparticulate System for Antimicrobial Effect

Herbal medicinal compounds have fewer side effects than modern drugs. Herbal materials are primary medicines and have strong antibacterial characteristics, thus most people throughout the world utilize them. Poor solubility, low bioavailability, instability in the biological environment, and substantial first-pass metabolism are some of the challenges associated with delivering plant/herbal medicinal compounds as pharmaceuticals. The use of appropriate nanotechnology for attachment or encapsulation can circumvent these drawbacks of herbal medications. To efficiently administer herbal medications, nanoparticulate formulations such as microemulsions, solid lipid nanoparticles, polymeric nanoparticles, liposomes, and proliposomes are being considered. This article aims to effectively examine the ability of herbal drugs that contain NP to combat microorganisms as well as a variety of herbal plants with antibacterial properties, including thyme, clove, garlic, mallow, chamomile, and mentha pulegium. This comprehensive analysis is timely and necessary since nanotechnology is a promising prospect in infectious disease treatment. Additionally, recent advances in producing herbal medicine formulations based on nanoparticle technologies are also summarised in this review article.