Assessment of diagnostic efficacy: High fluorescent cells combined with CEA, NSE, and Cyfra21-1 in Malignant Pleural Effusion Identification

HFC, CEA, NSE, and Cyfra21-1 are valuable diagnostic markers for MPE, with optimal cutoff values of 17.5 × 10<sup>6</sup>/L, 5.78 ng/mL, 10.97 ng/mL, and 34.61 ng/mL, respectively. The HFC+CEA combinations enhanced diagnostic sensitivity and clinical utility.

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Publication Details

Journal
Malawi Medical Journal
Published
2025-03-20
DOI
https://doi.org/10.4314/mmj.v37i1.5
Primary Topic
Pleural and Pulmonary Diseases
Type
article
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Assessment of diagnostic efficacy: High fluorescent cells combined with CEA, NSE, and Cyfra21-1 in Malignant Pleural Effusion Identification

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Assessment of diagnostic efficacy: High fluorescent cells combined with CEA, NSE, and Cyfra21-1 in Malignant Pleural Effusion Identification

Thomas Stuart Mughogho, Jie Zheng, Zhong Lin Wang, Ning Zhang, Xinchang Wang, Jian Hu, Aubrey Nothale, Dokani Michael Ndovi, Rashid Kaseka
article en

Abstract

HFC, CEA, NSE, and Cyfra21-1 are valuable diagnostic markers for MPE, with optimal cutoff values of 17.5 × 10<sup>6</sup>/L, 5.78 ng/mL, 10.97 ng/mL, and 34.61 ng/mL, respectively. The HFC+CEA combinations enhanced diagnostic sensitivity and clinical utility.

Malawi Medical JournalVol. 37(1)
Mzuzu University (MW)
Openalex Percentile: Top 87%
Pleural and Pulmonary Diseases
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