Interleukin-37 reduces lipopolysaccharide induced matrix metalloproteinase-9 in gingival epithelial cells
Gingival epithelial cells may contribute to tissue responses in periodontitis through the secretion of MMP-9 in response to PAMPs. Furthermore, IL-37 appears to have a potential role in modulating and reducing this response, as observed in the decreased MMP-9 expression following IL-37 co-stimulation.
Authors
- Muhammet Burak Yavuz
- Deniz Uckan
- Arzu Beklen (ORCID: https://orcid.org/0000-0002-1024-0257)
Institutions
- Boğaziçi University (TR)
- Eskişehir Osmangazi University (TR)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-04-25
- DOI
- https://doi.org/10.1186/s12903-025-06016-z
- Citations
- 1
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Helsingin Yliopisto