Safflower Extract Mitigates MIRI in Rats by Modulating TLR-4/NF-κB Signaling Pathway, Demonstrating Protective Effects
Safflower extract provides significant cardioprotection against MIRI by modulating the TLR-4/NF-κB-mediated inflammatory response. These findings suggest that safflower extract may be a potential therapeutic agent for mitigating the effects of myocardial ischemiareperfusion injury.
Authors
- Zhaoju Wang
- Yingfeng Deng (ORCID: https://orcid.org/0000-0003-1314-5105)
- Jing Yang (ORCID: https://orcid.org/0000-0001-8929-5391)
- Yue Dong (ORCID: https://orcid.org/0000-0003-4463-7858)
- Mingling Deng
- Aimaiti Julaiti
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Xinjiang Medical University (CN)
- Second Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Current Pharmaceutical Biotechnology
- Published
- 2025-04-24
- DOI
- https://doi.org/10.2174/0113892010356035250417022534
- Primary Topic
- Sunflower and Safflower Cultivation
- Type
- article
- Field-Weighted Citation Impact
- 0.00